Meridian Life Science Company Overview

Complete Range of Raw Materials for Immunological & Molecular Assay Manufacturers

ISO 13485 Certified Manufacturer

Solutions for human diagnostics, vet health, environmental, food testing & fraud prevention

Antigens, Antibodies & Blockers

• Infectious Diseases • Cardiac • Cancer • Vet Health • HAMA Blockers 150+ disease states

• Endocrine Disorders • Drugs of Abuse • Autoimmune • Allergens • Animal IgGs

ELISA, CLIA, Lateral Flow

Molecular Reagents

• qPCR/RT-qPCR Optimized Mixes • Lyo-Ready & Air-Dryable Mixes • Inhibitor Tolerant Mixes • DNA Polymerases • Reverse Transcriptases

• Bst Enzymes • High-Fidelity Enzymes • Extraction Controls • dNTPs

qPCR/RT-qPCR, dPCR, LAMP

Our products are used in commercial assays worldwide and their performance has been validated within approved FDA, CFDA, TGA, ANVISA and CE-marked assays.

www.MeridianLifeScience.com

Company Overview

43+ Years History | 700+ Employees | 14 Worldwide Locations

Cincinnati, USA Corporate Headquarters Diagnostic Tests

Luckenwalde, Germany PCR Enzymes Optimized Master Mixes dNTPs

Memphis, USA

Native & Rec-Antigens Antibodies & Blockers

Facilities Commercial Scale Manufacturing

Florida, USA

London, England

Monoclonal & Polyclonal Antibodies

PCR Enzymes Optimized Master Mixes

Beijing, China

Sydney, Australia Sales Marketing Logistics/Fulfillment

Sales Marketing Logistics/Fulfillment

70+ Global Markets | Nasdaq: VIVO

Solutions Tailored to a Wide Range of Industries From hi-throughput testing to specialized point-of-care devices, Meridian’s products support all types of assay development

Human Diagnostics

Vet Health

Blood Banking

Genetic Screening

Environmental

Water Testing

Food Testing

DNA Barcoding

www.MeridianLifeScience.com

Large portfolio covering 150+ disease states, disorders & other screening targets important to food and environmental monitoring. Antigens, Antibodies & Blockers

Viral Hepatitis

Cardiac

STD

Gastro

• H AV • H BV • H CV • H DV • H EV

• T roponin I, T • M yoglobin • B NP • N T-proBNP • C RP • P CT • C K-MB • D -Dimer • C ystatin-C • G alectin-3 • V itamin D • A po A,B,E • N SE • F ABP • S AH • M PO • F ibrinogen • E GF

• H SV-1, 2 • H IV-1, 2 • H PV • S yphilis • C hlamydia • N eisseria

•  H. pylori •  C. difficile • N orovirus • A denovirus • R otavirus

• C ryptosporidium • C ampylobacter •  E. coli

ToRCH & Childhood

Respiratory

• S almonella •  G. lamblia • A strovirus

• T oxo • R ubella • C MV • H SV-1,2 • R ubeola • E BV • M umps • C oxsackie • R otavirus • R SV • P arvo B19 • V ZV

• S ARS-CoV-2 •  M. pneumoniae •  C. pneumoniae • Influenza A,B • P arainfluenza •  L. pneumophila • R SV •  M. tuberculosis • S treptococcus • S taphylococcus • A denovirus

Veterinary

• A frican Swine Fever Virus (ASFV) • A vian Influenza • B orrelia •  Brucella abortus • C anine Distemper • F eline Immunodeficiency • F eline Leukemia • F oot-And-Mouth • C anine Heartworm • Infectious Bursal Disease • M arek Disease • N ewcastle Disease • C anine Parvovirus • R abies Virus • S erum Amyloid A (SAA) •  Trichomonas foetus • N ipah • T ransmissible Gastroenteritis

• L p-PLA2 • P APP-A

Microbial Detection

Hormones

Tropical

• L H, FSH, hCG, hGH, AMH

• Z ika • D engue 1, 2, 3, 4 • C hikungunya

•  C. jejuni •  E. coli

• C ortisol, Estradiol • Insulin, C-peptide • P rolactin • P rogesterone • P TH • P APP-A • T SH, T3, T4, ACTH • T hyroglobulin

• L egionella • S almonella •  B. anthracis • C lostridium • L isteria

• M alaria • C hagas

• L eishmaniasis • L eptospirosis • N ewcastle disease • Y ellow Fever • N ipah • J EV

• S treptococcus • S taphylococcus • C ryptosporidium •  G. lamblia

Cancer

Autoimmune

Allergens

Drugs of Abuse

• C A125 • C A15-3 • C A19-9 • C A72-4 • C A50 • C A242 • C EA • C yfra 21-1

• J o-1 • P CNA

• C at and Dog Allergen • H orse Allergen • D ust Mite • Alternaria alternate • T imothy Grass •  Platanus acerifolia • M ugwort

• A mphetamine • B arbital • B enzodiazepine • B uprenorphine

• p ANCA • c ANCA • S m Ag • d sDNA • L a(SSA) • R o(SSA) • H istone • G MB • C 1q • S cI-70 • S S-A • B 2-Gly-1

• C ocaine • C otinine • E DDP

• F entanyl • K etamine • K 2 • M DMA (Ecstasy) • M ethadone • M ethamphetamine • M orphine • N orketamine • O pium • O xycodone • P CP

• e rbB-2/HER2 • T hyroglobulin • A FP • E GFR

Blockers

• T RU Block™ • IgM Diluent • A nimal IgGs- Bovine, Chicken, Goat, Mouse, Rabbit, Sheep • H uman IgA, IgG, IgM, IgE • K appa Light chain • L ambda Light Chain • G oat Anti-Human IgG, IgM, IgA • G oat Anti-Mouse IgG

• H E4 • N SE • P IVKA II • P MA

• C athepsin G • C alprotectin

• P AP • P SA

• P SMA • S -100 • B 2M

• P henobarbital • P ropoxyphene • T HC

Assay Interference Blockers

Reduce interference from proteins in patient samples that could produce false results and lead to an incorrect diagnosis.

RF/IgG Absorbents IgM Diluent Blocks IgG antibody interference, HA & RF GAH IgG (Fc) Removes human IgG and IgG/RF complexes from serum prior to testing for IgM Ab HAMA, RF, HA All-in-1 Ultra Blocking TRU Block™ ULTRA

HAMA Blocker Mouse IgG

Interfering HA (e.g. HAMA) TRU Block

Blocks HAMA in double-mouse monoclonal sandwich assays

TRU Block

IgM RF

HA Blocker Animal IgGs

Detection Antibody (mouse origin) Capture Antibody (mouse origin) Antigen

Reduces interference caused by Heterophilic Antibodies (HA) present in a patient sample that can react with the PAb

Blocking Buffer

Blocking formulation with proprietary antibody that reduces HAMA, RF & HA

www.MeridianLifeScience.com

Range of specialized mixes for industry applications and individual components that can be tailored to any assay. Molecular Dx Reagents

qPCR & RT-qPCR Hot-Start Master Mixes

Lyo-Ready & Air-Dryable PCR & RT-qPCR Mixes • L yo-Ready qPCR Mix • L yo-Ready 1-Step RT-qPCRMix • L yo-Ready 1-Step RT-qPCR Virus Mix • A ir-Dryable qPCR Mix • Air-Dryable RT-qPCR Mix

• L ow DNA qPCR Mix • F ast qPCR Mix • H i-Throughput dUTP qPCR Mix • Inhibitor-Tolerant qPCR & RT-qPCR Mix • F ast 1-Step RT-qPCR Mix • L ow LOD 1-Step RT-qPCR Mix • Digital qPCR Mix

Bst for LAMP

DNA Polymerases

• Bst DNA Polymerase • H igh Concentrate Glycerol Free Bst

• T aq DNA Polymerase • T aq HS DNA Polymerase • G lycerol-Free Taq HS • Aptamer Taq HS (Glycerol-Free) • L ow DNA Taq HS • H igh-Fidelity Pfu • H igh-Specificity Pfu HS Mix

General MDx Reagents

• T issue Extract-PCR Buffers • U racil DNA Glycosylase * • P roteinase K Solution

• R Nase Inhibitor • T aq HS Antibody • d NTPs (Li & Na SaH)

Extraction Controls

• q PCR Extraction Control • RT-qPCR Extraction Control • VLP Extraction Control

NGS Enzymes & Buffers

• Library Quantification • Clean and Select Beads • E R Enzyme Mix • L igase

Reverse Transcriptases

• L yo-compatible MMLV-RT • R Nase-Tolerant MMLV-RT • M MLV-RT

*Unavailable in the USA

Properties & Applications for Master Mixes

Product Name / Description

Low DNA qPCR Mix Ideal for microbial and fungal detection Fast qPCR Mix Hot-Start mix for fast multiplex reactions Lyo-Ready qPCR Mix Lyophilization-ready formulation, includes lyo excipients Air-Dryable qPCR Mix Ready-to-use 4x qPCR mix ideal for oven or air-drying technologies Hi-Throughput dUTP Mix Formulated to remove background PCR product contamination Inhibitor-Tolerant qPCR Mix Amplification directly from crude lysates or inhibitor-rich samples such as urine, cerebral spinal fluid (CSF), saliva, blood and plants Inhibitor-Tolerant RT-qPCR Mix All-in-one, 4x master mix designed for RT-qPCR from crude samples such as sputum, stool and saliva. No sample extraction required Fast 1-Step RT-qPCR Mix Hot-Start mix for fast multiplex reactions Lyo-Ready 1-Step RT-qPCR Mix Lyophilization-ready formulation, includes lyo excipients Lyo-Ready 1-Step RT-qPCR Virus Mix Ideal for developing lyophilized multiplex assays detecting RNA viruses with a high secondary structure Air-Dryable RT-qPCR Mix Ready-to-use RT-qPCR Mix ideal for oven drying technologies Low LOD 1-Step RT-qPCR Mix Suitable for multiplex assays detecting viruses at very low levels

Chemical

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

Antibody

www.MeridianLifeScience.com

Life Discovered. Life Diagnosed. Point-of-Care Diagnostic Assays for Gastro, Pediatrics, Neonatal Care, Respiratory & Lead Poisoning

Meridian Life Science, Inc. 5171 Wilfong Road Memphis, Tennessee 38134-5611 USA 901-382-8716 / 800-327-6299 info@meridianlifescience.com orders@meridianlifescience.com

Connect with us:

张亮,医学博士 中国区业务发展总监/总经理

联系电话(美国):+ 1-312-405-3022 联系电话(中国):+ 86-18810208056 张亮:liang.zhang@meridianlifescience.com

www.MeridianLifeScience.com

02/21

Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8

meridianlifescience.com

Powered by