Meridian Cancer Catalog CHINESE

产品列表

α 1 抗胰蛋白酶 (A1AT)

缩略语表 6-His – Polyhistidine-tag Aff.Pur. – Affinity Purified, analyte-specific column Ag – Antigen Alk.Phos. – Alkaline Phosphatase conjugated product CLIA – Chemiluminescence Immunoassay CVD – Cardiovascular Disease DB – Dot Blot DFA – Direct Immunofluorescence Assay FC – Flow Cytometry FITC – Fluorescein conjugated product GST – Glutathione S-transferase HRP – Horseradish peroxidase conjugated product IB – Immunoblot

A1AT是一种主要在肝脏和乳房内生成的分泌糖蛋白。它是人血浆 内最丰富的的丝氨酸蛋白酶抑制剂。一些癌症与A1AT的减少有 关,如早期肝癌、肺癌膀胱癌和恶性肝癌。 单抗 • Does not cross-react with alpha 1 antichymotrypsin H45200M

α2巨球蛋白(A2M)

A2M是血清内的通用蛋白酶抑制剂,能够结合多种细胞因子和生 长因子。恶性肿瘤能够形成并释放蛋白质到循环中,包括A2M能 保护肿瘤免受免疫系统攻击。A2M的一个常见变体也被认为是阿 兹海默并风险增加的因素。 多抗 CATALOG SOURCE FORMAT APPLICATION L04330G Goat Monospecific IEP 抗原 A50114H • Native antigen from human plasma • > 95% pure (SDS-PAGE), lyophilized

ICC – Immunocytochemistry IEP – Immunoelectrophoresis IFA – Immunofluorescence Assay

IgG – Immunoglobin G IgM – Immunoglobin M IHC – Immunohistochemistry IP – Immunoprecipitation LF – Lateral Flow Lysate – Cells which have been lysed MAb – Monoclonal antibody Monospecific – Single band when tested by immunoelectrophoresis Neat – Whole, unpurified, undiluted antisera Neph – Product has been quality controlled by Nephelometry PAb – Polyclonal antibody Purified/IgG – Refer to the Certificate of Analysis regarding the extent of purification and the purification process used. RIA – Radioimmunoassay RID – Radial Immunodiffusion SDS-PAGE – Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis TIA – Product has been quality controlled by Turbidimetry WB – Western blot

α甲胎蛋白 (AFP)

AFP是有助于检测和诊断肝癌、睾丸癌和卵巢癌的肿瘤标志 物。AFP可以亲和电泳分为3种糖链异质体:L1、L2和L3。AFP-L3 针对恶性肿瘤。AFP-L3试验有助于评估发展中的肝细胞肝癌的风 险,尤其对于那些慢性干病患者,还能评估肝细胞肝癌对治疗的反 应。 单抗 • Does not cross-react with human serum albumin • Suitable for ELISA • MAbs produced in vivo (unless otherwise noted)

M01254M M01255M M86304B M86641M M86501M

* Also works in LF assays

* Biotin conjugated

* Reacts with AFP Receptor, suited to blocking AFP/ AFP-binding

抗体配对 • Suitable for ELISA • MAbs produced in vivo (unless otherwise noted) CAPTURE DETECTION H45610M H45301M

* Does not react with human albumin, ferritin, hCG or PSA

MAM01-210 MAM01-301 M86304M M86641M

* Does not react with human albumin

9 | Cancer & Tumor Markers for Assay Development 用于开发肿瘤标志物体外诊断试剂的原料 9

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