Meridian Cancer Catalog CHINESE

弹性蛋白酶 弹性蛋白酶是一种丝氨酸蛋白酶,特别是嗜中性粒细胞形式的弹 性蛋白酶是218氨基酸长,2天冬酰胺链糖链。它由嗜中性粒细胞 和巨噬细胞在炎症期间分泌用来摧毁细菌和宿主住址。研究表明 嗜中性粒细胞弹性蛋白酶可以加速癌症恶化,肿瘤组织内的免疫 反应嗜中性粒细胞弹性蛋白酶是乳腺癌和肺癌患者独立的预后指 标。 抗原 A01683H • Native antigen from human neutrophils • Suitable for use in ELISA and WB • 90% pure SDS-PAGE (Chromatography) A50145H • Native antigen from human neutrophils • > 95% pure (SDS-PAGE), lyophilized 多抗 CATALOG SOURCE FORMAT APPLICATION K90052C Sheep Purified WB 表皮生长因子 (EGFR) EGF是一种与它的受体EGFR结合刺激细胞生长、增殖和分化的生长 因子。EGF调节异常和导致EGFR过表达的突变与一些癌症有关,包 括肺癌、乳腺癌、肛门癌以及胶质母细胞瘤。许多治疗方法以 EGFR为目标如西妥昔单抗和帕尼单抗。 单抗 • Suitable for use in ELISA (unless stated otherwise) • Lyophilized • Produced in cell culture (unless stated otherwise) K67138M * R ecognizes the C-terminus a.a. 1165-1186, also works in IB, ICC and IP P24100M * D oes not cross-react with v-erb-B, also works in IHC and FC P24200M * D oes not cross-react with v-erb-B, also works in IHC and FC K67190M * R ecognizes site phosphorylated at Serine 1047, also works in IB, ICC and IP K67902M * R ecognizes site phosphorylated at Tyrosine 1173, also works in IB, ICC and IP K67123M * R ecognizes site phosphorylated at Tyrosine 845, also works in IB 抗原 VTI880 • Recombinant EGF (P. pastoris)

erbB-2, HER2/neu 受体酪氨酸蛋白激酶erbB-2通常称为HER2(人类表皮生长因子2 ),是人类表皮生长因子家族成员。HER2的过表达在特定侵袭 性乳腺癌的发展和恶化中发挥着重要作用。大约15%的新诊断乳 腺癌为HER 2阳性,HER2检测的目的时间别患者是否能从HER2 靶向疗法中获益,如曲妥单抗、拉帕替尼、帕托珠单抗和TDM1 单抗

• Reacts with peptide ILDV4 • Suitable for use in ELISA • Produced in vivo M01296M

* Reacts with peptide ILDV4 (dephosphorylated) * Reacts with peptide ILDV4 (phosphorylated) * Reacts with peptide ILDV2 (dephosphorylated) * Reacts with peptide ILDV2 (phosphorylated)

M01297M M01298M M01299M

抗原 R01605

• Recombinant (HEK293 cells) • Suitable for use in ELISA •  95% Pure (SDS-PAGE), lyophilized, contains a His-tag

细胞粘附分子 (EpCAM) 该物质是参与细胞间粘着、信号传播、细胞迁移、增殖和分化的 糖蛋白。它的表达限制于健康个体的正常上皮细胞,但是在癌症 中它的表达分布随着癌症的不同而变化。它被视为肿瘤先关抗原 并在多种癌症中发挥预后标志物的作用。 单抗 • Suitable for use in ELISA and WB • Produced in vivo M01310M * Recognizes a.a. 116-242 Factor H (Beta 1H) H因子是补体活化家族的调节剂成员,它是补体调控蛋白。异常的 H因子活性的临床意义包括中风、精神分裂和癌症。尤其是它可以 作为膀胱癌的肿瘤标志物。 多抗 CATALOG SOURCE FORMAT APPLICATION K90030C Sheep Purified DD,IE,IEP

• Suitable for use in WB • 95% pure (SDS-PAGE)

• Recombinant EGF (P. pastoris) • Suitable for use in WB • > 95% pure (SDS-PAGE)

VTI882

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