Rubella IgM Population Study
In-house ELISA using purified Rubella Antigen (Product #6076) 100 Normal Samples using Standard Ag.
In-house ELISA using Rubella IgM MAX™ Antigen (Product #6300) 100 Normal Samples using Glycoprotein Ag.
90 100
90 100
0 10 20 30 40 50 60 70 80
0 10 20 30 40 50 60 70 80
Positive Cutoff @ 1.0 REV
Positive Cutoff @ 1.0 REV
0
0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 1.8 2.0
0
0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 1.8 2.0
REV Range (low limit)
REV Range (low limit)
Rubella IgM Max exhibits greater specificity for Rubella IgM antibodies compared Antigen #6076. It does not bind to lower-affinity antibodies which might be non-Rubella but related viruses or other proteins that cause cross-reactivity in IgM diagnostic assays.
In-house ELISA using Rubella IgM MAX™ Antigen (Product #6300) Serum Diluent with urea. 100 Normal Samples using Glycoprotein Ag.
90 100
0 10 20 30 40 50 60 70 80
Positive Cutoff @ 1.0 REV
0
0.2 0.4 0.6 0.8 1.0 1.2 1.4 1.6 1.8 2.0
REV Range (low limit)
Use of urea increases the stringency of binding by removing reactivity from low affinity antibodies.
Life Science Division 5171 Wilfong Road, Memphis, TN 38134 901-382-8716 • 800-327-6299 • info@meridianlifescience.com
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May 2019
www.meridianbioscience.com/lifescience
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