LAMP
SPEED: Superior specificity and quicker time-to- results (TTR) detection for viral and bacterial targets
SENSITIVITY: Superior assay sensitivity and reproducibility with lower TTR and delayed NTC
60
60
50
50
40
40
30
30
20
20
10
10
0
0
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
Sample
NTC
HBV
HSV2
EBV
T. vaginalis
M. pneumoniae
HCV
HIV-1
DENGUE 1
WNV
Zika
Meridian Lyo-Ready Direct DNA LAMP Blood | NEB WarmStart ® | Thermo SuperScript ™
INHIBITOR TOLERANCE: High inhibitor tolerance and fast amplification to deliver quicker time-to- results (TTR) in inhibitor-rich samples. SuperScript ™ IV RT-LAMP Master Mix ( yellow ) using the same primers and DNA/RNA for five different targets as shown in the graph. Error bars represent the standard deviation across three technical replicates. For more detailed information, refer to the product flyer. The performance of Lyo-Ready Direct LAMP Blood Mix (MDX124, blue ) were compared against NEB WarmStart ™ LAMP kit ( grey ) and Thermo
The performance of Lyo-Ready Direct LAMP Urine Mix (MDX154, Blue ) were compared against NEB WarmStart ™ LAMP kit ( grey ) and Thermo SuperScript ™ IV RT-LAMP Master Mix ( yellow ) using the same primers and DNA/RNA for five different targets as shown in the graph. Error bars represent the standard deviation across three technical replicates. For more detailed information, refer to the product flyer.
COMPATIBILTIY: Compatible with lyophilization without any loss in sensitivity and speed
ADV
HSV2
50
70 60 50 40 30 20 10 0
70 60 50 40 30 20 10 0
40
30
20
10
0
1000 copies/rxn
500 copies/rxn
100 copies/rxn 10 copies/rxn
0% inhibitor
30% saliva
30% UTM+ Sputum
0% inhibitor
30% saliva
30% UTM+ Sputum
30% VTM
NTC
30% VTM
NTC
Meridian Lyophilized | NEB WarmStart®
Meridian Lyophilized | Meridian Air-dried | NEB WarmStart®
Lyophilized Lyo-Ready Direct DNA LAMP Saliva (MDX134, blue ) was compared to liquid NEB WarmStart ™ ( orange ) for their inhibitor tolerance to a range of inhibitors in amplification reactions detecting inactivated Adenovirus (ADV) or Herpes simplex virus 2 (HSV-2). Error bars represent the standard deviation across four technical replicates. For more detailed information, refer to the product information sheet.
1,000, 500, 100 and 10 copies of Emesvirus (MS2) were amplified using Air- Dryable ™ RNA/DNA LAMP (MDX118) in an air-dried ( red ) format, liquid ( blue ) format, or using NEB WarmStart ™ ( orange ) using the same primers and probes. Error bars represent standard deviation over 4 technical replicates. Fore more detailed information, refer to the product flyer.
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