TRIMERIC SPIKE ANTIBODIES
For use in lateral flow antigen detection COVID-19 assays Designed to work on saliva samples (no lysis required) Novel antibody pair to the trimeric form of the Spike 1 surface glycoprotein, recognizes both the G614 and D614G strains Using a mixture of detection antibodies Cat# 9565 and #9551 in a 1:1 ratio creates a synergistic effect that increases assay sensitivity in ELISA Recognizes a linear epitope - binding is not conformation-dependent Sensitivity of approx. 300 pg/mL in ELISA Does not cross-react with SARS-CoV, HCoV-229E, HCoV-HKU1, HCoV-NL63 and HCoV-OC43
Cat# 9550
MAb to SARS-CoV-2 S1 (Trimeric)
Cat# 9551
MAb to SARS-CoV-2 S1 (Trimeric)
Cat# 9565
MAb to SARS-CoV-2 S1 (Trimeric)
*9551 and 9565 can be used together in a 1:1 ratio to increase assay sensitivity in ELISA
SYNERGISTIC EFFECT OF CAT# 9551 AND 9565 ENHANCES DETECTION OF SARS-COV-2 TRIMERIC SPIKE PROTEIN
MAb sandwich ELISAs were compared for their ability to detect recombinant SARS-CoV-2 across 4 serial dilutions (10 ng/mL – 0.3 ng/mL). One assay used Cat# 9550 as the capture and Cat# 9551 as the detection antibody a second assay used Cat# 9550 as the capture and Cat# 9565 as the detection antibody and a third assays used Cat#9550 as the capture and Cat#9551 and Cat#9565 together in a 1:1 ratio as the detection antibodies. Using Cat# 9551 and 9565 in combination creates a synergistic effect that results in an enhanced detection of SARS-CoV-2 Trimeric Spike protein across all concentrations.
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