Immunoassay Blocking Agents: Reducing False Results

CHOOSING THE RIGHT BLOCKER Tailored Blocking Solutions for Every Stage of Development

Accurate immunoassays depend not only on high-quality antibodies, but also on effective blocking strategies that minimize background and interference—especially from HAMA, rheumatoid factor (RF), and other heterophilic antibodies. Whether you are developing ELISAs, lateral flow assays (LFA), or chemiluminescent immunoassays (CLIA), Meridian’s blockers are your first line of defense. Our portfolio includes trusted solutions such as: • Mouse Serum • Mouse IgG • TRU Block TM Series (TRU Block TM , TRU Block TM 2, TRU Block TM 3) • K-BLOCK TM Unsure which blocker fits your assay? Scan to learn more and order a sample pack

Explore Meridian’s complete range of interference-blocking reagents:

BLOCKER

BLOCKER TYPE

INTERFERENCE TYPE

ASSAY COMPATIBILITY

Passive Passive

HAMA, non-specific binding proteins ELISA, LFA

Mouse Serum

HAMA

ELISA, CLIA ELISA, CLIA

Mouse IgG

TRU Block TM

Universal (Active + Passive)

HAAA, RF, HA

ELISA, CLIA, LFA

TRU Block TM 2 TRU Block TM 3

ELISA, CLIA

Active

HAAA, RF, HA

ELISA, CLIA, LFA

K-BLOCK TM

Need help selecting the right blocker? Visit our Blocker Resource Page or contact our technical team for personalized guidance.

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