Tiered Blocking for Every Challenge TRU Block TM is Meridian’s flagship line of interference blockers, designed to address a wide range of assay challenges. All TRU Block TM formulations consist of varying combinations of mouse IgG and a proprietary active blocker. Each version is optimized for different levels of interference and assay sensitivity. TRU Block TM Series
UNDERSTANDING THE DIFFERENCES BETWEEN TRU BLOCK TM FORMULATIONS
TRU Block TM
TRU Block TM 2
TRU Block TM 3
• Heavier on the active blockers, lighter on the mouse IgG • Validated on ELISA and CLIA
• A balance between active blockers and mouse IgG • Validated on ELISA, CLIA, and LFA
• Heavier on the mouse IgG, lighter on the active blockers • Validated on ELISA and CLIA
Proprietary Active Blocker Mouse IgG
All three formulations are universal blockers and work against a range of interferences including HA, HAMA, and RF.
WHY CHOOSE THE TRU BLOCK TM SERIES? • Proven performance across platforms • Minimal impact on assay kinetics • Available in bulk and customizable formats
ORDERING INFORMATION HAMA & RF Blockers
Cat. No. A66800H A66802H A66803H
TRU Block TM TRU Block TM 2 TRU Block TM 3
The TRU Block TM Series demonstrates superior HAMA and RF blocking over mouse IgG and other commercial active blockers
( A ) HAMA INTERFERENCE SUPPRESSION
( B ) RF INTERFERENCE SUPPRESSION
Mouse IgG
TRU Block TM
TRU Block TM 2
TRU Block TM 3
Competitor (Active)
Blocker Concentration ( μ g/mL)
Blocker Concentration ( μ g/mL)
Percentage of ( A ) HAMA interference and ( B ) RF interference blocked by Mouse IgG , each of the TRU Block TM Series , and the leading competitor active blocker , at various concentrations of blocker. Higher blocking (%) indicates better blocking performance. The TRU Block TM Series outperforms the leading competitor at lower concentrations in (A), and at all concentrations in (B).
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