Immunoassay Blocking Agents: Reducing False Results

K-BLOCK TM

Broad-Spectrum Blocking Power & Animal-Free

K-BLOCK TM is a proprietary blend of recombinant immunoglobulins and proteins that offers broad-spectrum active blocking against a wide range of interfering substances, including: • Heterophilic antibodies • Rheumatoid factors • HAAAs (e.g., HAMA, HAGA, HARA, etc.) ORDERING INFORMATION K-BLOCK TM BN1200

KEY FEATURES • Effective across multiple species and sample types • Ideal for lateral flow and point-of-care assays • Recombinant, animal-free blocker

APPLICATIONS

Lateral flow devices ELISA and CLIA platforms High-throughput screening

K-BLOCK TM demonstrates superior HAMA and RF blocking over mouse IgG and other commercial active blockers

( A ) HAMA INTERFERENCE SUPPRESSION

( B ) RF INTERFERENCE SUPPRESSION

Mouse IgG

K-BLOCK TM

Competitor (Active)

Blocker Concentration ( μ g/mL)

Percentage of ( A ) HAMA interference and ( B ) RF interference blocked by Mouse IgG , K-BLOCK TM , and the leading competitor active blocker , at various concentrations of blocker. Higher blocking (%) indicates better blocking performance. K-BLOCK TM outperforms the leading competitor at lower concentrations in (A), and at all concentrations in (B).