Cardiac & Metabolic Markers Catalog

Monoclonals • Reacts with human free C-peptide and Proinsulin • Suitable for use in ELISA and RIA • Produced in vivo E86588M • Reacts with C-peptide • Suitable for use in ELISA and RIA E86710M MHP18-601 MHP18-6014 * Biotin conjugated

sCD40 Ligand (sCD40L)

A member of the TNF superfamily primarily expressed on activated T cells. Studies suggest that sCD40L may be at the heart of the atherosclerotic process, specifically playing a role in the inflammatory aspects of atherosclerotic lesion progression, thrombosis and restenosis. Monoclonals • Suitable for use in ELISA and WB • Can be used for detection of human sCD40L in serum P86210M

Collagen Type I & III

C-Reactive Protein (CRP)

Increased myocardial collagen accumulation is present in almost every cardiac disease and plays an important role in the reduced heart function. N-terminal and C-terminal propeptides of Collagen Type I and III are the two major collagen types in the heart and reflect collagen synthesis and degradation. Their role as serum biomarkers for the diagnosis of cardiac fibrosis is being studied. Monoclonals • Specific for both native and heat denatured human Collagen Type I • Suitable for ELISA and IHC M1A340M Polyclonals CATALOG SOURCE FORMAT APPLICATION Collagen Type III T40233R Rabbit Purified EIA,IFA,IHC Antigens A33123H • Native Human Collagen Type III • Sourced from placental villi, > 90% pure (SDS-PAGE) • Suitable as a immunoassay standard and for antibody production

CRP is mainly used as a maker of inflammation. High- sensitivity CRP assays can be used for determining the risk of cardiovascular disease, heart attacks, and stroke. Antibody Pairs • Suitable for use in ELISA, high sensitivity • MAbs produced in vivo CAPTURE DETECTION M86005M M01239M * Recognizes CRP with or without Ca2+. M01243M M01239M * Recognizes CRP with or without Ca2+. M01331M M01330M Monoclonals • Recognizes CRP with or without the presence of Ca 2+ • Suitable for use in ELISA • Produced in vivo M01238M * Can also be used in IHC and WB

M66112M M66113M M86007M M86842B

* Can also be used in IHC

* Biotin conjugated

M86842M • Recognizes CRP • Suitable for use in ELISA (Unless otherwise specified) • Produced in vivo M01319B * Biotin conjugated

C-peptide & Proinsulin

M01319M M01295M

C-peptide is a combination of amino acids that are a by-product of insulin and the level of this protein indicates how much insulin the pancreas is producing. Studies have shown an association between serum C-peptide levels and risk of cardiovascular-related disease and coronary artery-related mortality among adults without diabetes.

* No applications have been tested

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