Cardiac & Metabolic Markers Catalog

Creatine Kinase MM (CK-MM) continued

D-Dimer continued Antibody Pairs • Suitable for use in ELISA and WB • Reactive with D-Dimer and other fribin degradation products • MAbs produced in vivo CAPTURE DETECTION N01270M N01269H * Does not cross-react Fragment D or E, also suitable for LF N01273M N01274M * Does not cross-react with Fibrinogen

Antigens VTI850

• Recombinant (P. pastoris) , Isoenzyme Type I • Full length protein without the C-terminal lysine on both subunits • Suitable for use in WB and ELISA • Recombinant (P. pastoris) , Isoenzyme Type I • Identical amino acid sequence to native protein • Suitable for use in ELISA

VTI820

N86304M N86925M N86304M N86043M Antigens A01408H

A38925H

• Native antigen from human heart, lyophilized

Cystatin C

• Native antigen from human plasma • > 90% pure (SDS-PAGE and gel-scanning) • Native antigen from human plasma • Suitable for ELFA • 95% pure (SDS-PAGE) • Native antigen from human plasma • > 90% pure (SDS-PAGE and gel-scanning), lyophilized

Traditionally used as a biomarker of kidney function, it has recently been studied for its role in predicting new onset or deteriorating CVD. In different cardiovascular conditions, Cystatin C is a sensitive marker for renal dysfunction, a predictor of the development of heart failure, and is independently associated with subsequent CVD and outcome. Antibody Pairs

A01463H

A86870H

• Suitable for use in ELISA • MAbs produced in vivo CAPTURE DETECTION H86023M H86013M Antigens A01419H

Epidermal Growth Factor (EGF) EGF is a growth factor with potential use as cardiac biomarker due to its role in the proliferation of cardiac stem cells. Research suggests that the human heart has an endogenous reserve of cardiac stem cells (CSCs) which can be activated by various growth factors to reconstitute injured myocardium. EGF has shown to significantly promote the proliferation, migration, and wound healing activities of these CSCs in comparison to the other growth factors. Antigens VTI880 • Recombinant (P. pastoris)

• Native antigen from human urine

D-Dimer

D-dimer is a marker of fibrin turnover and elevated levels are indicative of the presence of a clot and have been reported in deep vein thrombosis, pulmonary embolism, disseminated intravascular coagulation, acute aortic dissection, myocardial infarction, malignant diseases, obstetrical complications, third trimester of pregnancy, and surgery. It is a marker for the early diagnosis of acute coronary syndromes and can be used in addition to traditional assessment for myocardial infarction. Monoclonals • Does not cross-react with fibrinogen and D-monomer (unless noted otherwise) • Suitable for use in ELISA and WB N86925M * Reacts with high molecular weight fibrin degradation products N86925B * Biotin conjugated

• Suitable for use in WB • >95% pure (SDS-PAGE)