Cardiac & Metabolic Markers Catalog

Lipoproteins HDL, LDL,VLDL Receptor Lipoprotein diagnostics, such as LDL cholesterol and HDL cholesterol, help to diagnose dyslipidemia which is an important risk factor for cardiovascular disease and type II diabetes. Monoclonals • MAb to LDL Receptor-Related Protein (LRP) • Will not block ligand binding • Suitable for use in ELISA, WB, IHC, and FC

Hemoglobin A1c (HbA1c) As glucose circulates in the blood, some of it spontaneously binds to hemoglobin to form hemoglobin A1c (HbA1c). The development of specific diabetes complications correlates with glycated haemoglobin (HbA1c), the most accepted measure of chronic glycaemia. Monoclonals

• Suitable for use in sandwich ELISA • Does not cross-react with HbA10 • Produced in vivo H01331M

H63650M Antigens A95132H

* Can also work in indirect ELISA (antigen capture)

• Native HDL from human normolipidemic plasma • Devoid of VLDL, IDL and LDL • Ultracentrifugation at density 1.063–1.210 • Native HDL 2 (HDL2) Subfraction from human normolipidemic plasma • Devoid of VLDL, IDL, LDL, and HDL3 • Ultracentrifugation density at 1.063- 1.125 • Native HDL 3 (HDL3) Subfraction from human normolipidemic plasma • Devoid of VLDL, IDL, LDL, and HDL2 • Ultracentrifugation density at 1.120–1.21g/mL • Reconstituted HDL from human plasma • A complex of human Apolipoprotein A-I and 1-palmitoyl-2-oleoyl phosphatidylcholine prepared at a molar ratio of 1 to 100 by the cholate removal method

H01388M Antigens A01273H

* Can also work in WB

• Native antigen from human erythrocytes • > 96% HbAlc (HPLC analysis using a Mono S Column)

A95322H

Interleukin 8 (IL-8) IL-8 is a neutrophil chemokine produced by macrophages, lymphocytes, epithelial cells and endothelial cells, and promotes neutrophil chemotaxis. Studies in patients with CAD have demonstrated that IL-8 may predict cardiovascular events independent of the other cytokines and high sensitivity CRP. Antigens A42280H • Recombinant (E. coli), a.a. 1-72 • > 98% pure (HPLC, FPLC and reducing and non-reducing SDS-PAGE) A42208H • Recombinant (E. coli) , a.a. 1-77 • > 98% pure (HPLP and SDS-PAGE)

A95332H

A34275H

A34013H

• Native VLDL from human plasma • Devoid of IDL, LDL, and HDL • Purification by ultracentrifugation at density 1.006

Lectin-like Oxidized LDL Receptor-1 (sLOX) Soluble Form

A major endothelial receptor for oxidized low-density lipoprotein which is believed to play a role in atherosclerosis. Its expression is induced in pro-atherogenic settings including hypertension, hyperlipidemia, and diabetes, and it accumulates in therosclerotic lesions where it has been strongly linked to plaque rupture. Specifically sLOX-1 levels are elevated in acute coronary syndrome at an early stage, suggesting its usefulness as an early diagnostic marker of acute coronary syndrome. Monoclonals • Specific for human recombinant sLOX-1 (a.a. 58-273) • Suitable for use in ELISA and WB • Produced in vivo H86922M