Cardiac & Metabolic Markers Catalog

Product list | Continued

S-100

Serum Amyloid A (SAA)

The S-100 family of proteins are involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. Studies have shown that serum measurements of S100-beta maybe useful for the diagnosis and prognosis of acute stroke. Monoclonals • Produced in vivo MEM24-211 * Works in IHC Q86403M * Recognizes S-100 (beta-beta) and S-100 (alpha-beta), works in WB Antibody Pairs • Suitable for use in ELISA and IP • MAbs produced in vivo CAPTURE DETECTION Q86006M Q86610M * Specific for S-100 beta-beta and alpha-beta Q86003M Q86610M * Specific for S-100 beta-beta and alpha-beta Antigens A86809H • Native antigen from human brain • Contains beta-beta homodimer (S-100b) and alpha-beta heterodimer (S-100a) • > 95% pure, lyophilized • Suitable for ELISA, as an immunogen for antiserum production and tracer for iodination A86289H • Native S-100b from human brain • > 95% pure, lyophilized • Suitable for ELISA, as an immunogen for antiserum production and tracer for iodination

SAA is a sensitive marker of acute inflammation that has been implicated in several chronic inflammatory diseases such as amyloidosis, atherosclerosis, and rheumatoid arthritis. A systemic inflammation (manifested by high SAA levels) may promote atherosclerotic plaque destabilization, in addition to exerting a possible direct effect on atherogenesis. Antibody Pairs • Suitable for use in ELISA and WB • Recognizes native and recombinant human SAA • MAbs produced in vivo CAPTURE DETECTION H01381M H01383M H01382M H01384M

H86177M H86180M H86180M H86177M H86177M H86178M H86178M H86177M Polyclonals CATALOG

SOURCE FORMAT APPLICATION

H01379R Antigens R01619

Rabbit

Purified

EIA, IEP

• Recombinant (E. coli) • 122 a.a. long with N-terminal His tag • Suitable for use in ELISA

Stromal Cell-Derived Factor 1 alpha (SDF-1 α ) SDF-1 α is a chemokine produced in two forms, SDF-1 α and SDF-1 β by alternate splicing of the same gene. Studies have found increased levels of SDF-1 α in several cardiac diseases. It has been suggested to be a prognostic marker in atrial fibrillation.

S-Adenosyl-Homocysteine (SAH)

SAH is formed by the demethylation of S-adenosyl-L-methionine (SAM) and acts as an intermediate in the synthesis of cysteine and adenosine. It is elevated in CVD and serves as an indicator of various diseases involving vascular dysfunction. Polyclonals CATALOG SOURCE FORMAT APPLICATION K01395C C. Eggs Aff.Pur. N/A

Antigen A42028H

• Recombinant (E. coli) • >98% pure (RP-HPLC and SDS-PAGE), lyophilized

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18 | Cardiac & Metabolic Markers for Assay Development Cardiac & Metabolic Markers for Assay Development

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