Cardiac & Metabolic Markers Catalog

Vitamin D Vitamin D is a fat-soluble precursor of the steroid hormone calcitriol that is essential for bone health and mineral metabolism. Total Vitamin D assays measure the level of both 25 OH Vitamin D3 (calcidiol) and 1,25-Dihydroxy Vitamin D3 (calcitriol). Serum 25 OH Vitamin D3 is the most stable circulating form of vitamin D and a low blood level suggests that a person is not getting enough exposure to sunlight or enough dietary vitamin D. 1,25-Dihydroxy Vitamin D3 regulates the expression of hundreds of genes and a low level is indicative of kidney failure. Antibody and Antigen Pairs ANTIBODY ANTIGEN K01214M A01697B *Lateral Flow K01214M A01698B *ELISA and RIA Monoclonals

Troponin T-Cardiac (cTnT) continued Monoclonals • Suitable for use in ELISA and IP • Not cross-reactive with skeletal Troponin T • Produced in vivo EPITOPE BINDING H86914M a.a. 146-160 Antigens A86813H • Native antigen from human heart • >98% pure (SDS-PAGE)

• Suitable for use in ELISA, as antigen for antisera production, and as a tracer for iodination

Tumor Necrosis Factor alpha (TNF-alpha) TNF-alpha is a cytokine involved in systemic inflammation and implicated in post-ischemic myocardial dysfunction and heart failure. Concentrations of TNF-alpha reflect the impairment of cardiac and renal function in patients with CAD. Metabolic syndrome and diabetes are also associated with higher plasma concentrations of TNF-alpha and its receptors. Antibody Pairs • Suitable for use in ELISA and IHC • Inhibits the biological activity of TNF-alpha in various biological fluids CAPTURE DETECTION H86410M H86650M participates in the regulation of salt and water homeostasis. It is synthesized as prohormone and requires proteolytic processing similar to the other natriuretic peptides. It is also activated in heart failure, but acts on a different cyclic GMP pathway to ANP and BNP. Polyclonals CATALOG SOURCE FORMAT APPLICATION D01240R Rabbit Neat EIA,IHC,RIA,WB * D01240R is specific for the circulating form Uroguanylin Uroguanylin is a novel natriuretic hormone system and

• Suitable for use in ELISA • Produced in cell culture K24123M

*MAb to 1,25 (OH)2 Vitamin D3

K24124M

*MAb to 25-OH Vitamin D3 Lyophilized *MAb to 25-OH Vitamin D3 Liquid

K24124M-LQ

Antigens A01694D

• 99% Pure (HPLC) • 25-OH Vitamin D3 BSA Conjugate

A01409H

• > 99% Pure (HPLC) • 1,25-Dihydroxy Vitamin D3

A50674H

• > 95% Pure (SDS-PAGE) • Vitamin D Binding Protein (GC Globulin)