Immunoassays for drug-testing are generally divided into forensic (DOA assays) and clinical products (TDM serum assays). Due to the differences in applications there are distinct design, technical capabilities and regulatory approval processes for each type. Meridian offers a range of drug testing reagents designed to produce accurate and precise results for both qualitative and quantitative assays.
Drug Testing Reagents for Commercial Assay Development Antibodies and antigens designed for assays detecting therapeutic drugs and drugs of abuse
Immunoassays for drug-testing are generally divided into forensic (DOA assays) and clinical products (TDM serum assays). Due to the differences in applications there are distinct design, technical capabilities and regulatory approval processes for each type. Meridian offers a range of drug testing reagents designed to produce accurate and precise results for both qualitative and quantitative assays.
DRUG TESTING REAGENTS > DRUGS OF ABUSE (DOA)
> THERAPEUTIC MONITORING > ANTIBIOTICS > OTHER DRUG TESTING REAGENTS
Cannabinoids CNS stimulants Depressants Hallucinogens Opiates
About drug testing
Drug abuse testing traditionally refers to the practice of testing for drugs including depressants, hallucinogens, CNS stimulants, opiates, cannabinoids, and phencyclidine (PCP). These tests have expanded in recent years to include (1) workplace, military and school testing for drugs of abuse (DOA), (2) screening in sports for the use of performance enhancing compounds, and (3) the emergency-room in order to diagnose possible overdose situations. In all of these areas, the testing method is qualitative only and is typically dependent on a urine or saliva sample as the testing specimen. Specifically, these types of assays are designed to determine if an individual is or is not taking DOA or non-prescribed medications.
Another use of drug testing is to monitor drug pharmacokinetics in order to help physicians provide the best treatment to their patients. With most medications, a certain dosage level of the drug (the therapeutic range) is required to obtain the desired effect. The goal of therapeutic drug monitoring (TDM) is to optimize the dose and clinical outcome for each patient. Some key differences in the TDM testing method compared to DOA are (1) the diagnostic specimen is typically serum instead of urine, saliva or hair, (2) the results are quantitative and need to be accurate and precise over a large concentration range, and (3) the tests are designed for use in hospital laboratories as opposed to rapid point-of-care.
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Antibody & drug conjugate pairs
> All pairs are suitable for use in ELISA or Lateral Flow assays > Various conjugates available in different hapten: protein ratios
ANTIGEN CAPTURE
MAb DETECTION
ANTIGEN CAPTURE
MAb DETECTION
Y01298B (BSA) METHADONE
Y01301B (BSA) Y01287B (BSA) AMPHETAMINE
G01284M
G01301M or G01302M
G01282M or G01284M
METHAMPHETAMINE
Y01294B (BSA)
G01295M or G01296M or G01297M
BARBITAL
Y01285B (BSA)
G01283M or G01285M
MORPHINE
BENZODIAZEPINE
Y01295B (BSA 40:1)
G01298M or G01299M or G01300M G01298M or G01299M or G01300M G01298M or G01299M or G01300M
Y01290B (BSA)
G01290M
BENZOYLECGONINE (MAIN COCAINE METABOLITE)
Y01296B (BSA 40:1)
Y01293B (BSA)
G01294M or G01292M G01293M or G01292M
Y01297B (BSA 70:1)
Y01292B (BSA)
BUPRENORPHINE
Y01299B (BSA) OXYCODONE
Y01291B (BSA)
G01291M
Saliva & Urine
G01303M or G01304M
MDMA (ECSTACY)
THC
G01267B (BSA)
G01265M
Y01268B (BSA)
G01286M
Illicit drugs
CANNABINOIDS
HALLUCINOGENS
CNS STIMULANTS CONT.
THC MAD12-066 (MAb) G01286M (MAb) G01238M (MAb) G82920M (MAb) G82922M (MAb) Y01273B
KETAMINE G01255M (MAb) G01269M (MAb) G01270M (MAb) Y01269B
BENZOYLECGONINE/ COCAINE G45020M (MAb)
B
G45132M (MAb) G82911M (MAb) G01277M (MAb) G01292M (MAb) G01293M (MAb) G01294M (MAb)
B+C B+C
(BSA conj) (BSA conj)
Y01241B Y01270B
B+C B+C
(BGG conj) (BGG conj) (BSA conj)
(BSA conj) HS
Y01274B Y01268B K2 Y01302B
MDMA G01265M (MAb) G01266M (MAb) G01267B
B
Y01292B Y01293B Y01277B
(BSA conj) B (BSA conj) B (BSA conj) C
(BSA conj)
(BSA conj)
COTININE G01257M (MAb) COTININE-4 F82419R (PAb) F82451R (PAb) CAFFEINE G45110M (MAb) METHAMPHETAMINE G35913M (MAb) G82913M (MAb) G01271M (MAb) G01295M (MAb) G01296M (MAb) G01297M (MAb) Y01294B
OPIATES
DEPRESSANTS BARBITAL G01283M (MAb) G01285M (MAb) Y01285B (BSA conj)
METHADONE G01301M (MAb) G01302M (MAb) Y01280B
(BGG conj) (BSA conj)
Y01298B
PHENOBARBITAL Y82611A BENZODIAZEPINE G01290M (MAb) Y01290B
EDDP Y01306B Y01305B OPIUM Y01275B
(BSA conj)
(BSA conj) (BGG conj)
(BSA conj) (BGG conj) (BGG conj) (BGG conj) (BGG conj)
(BSA conj)
Y01281B Y01282B Y01283B Y01284B
MORPHINE G31263M (MAb) G01276M (MAb) G01298M (MAb) G01299M (MAb) G01300M (MAb) Y01276B
(BSA conj) (BSA conj)
Y01271B
CNS STIMULANTS
(BSA conj) (BSA conj) (BSA conj) (BSA conj)
AMPHETAMINE G01282M (MAb) G01284M (MAb) G01289M (MAb) Y01287B
Y01295B Y01296B Y01297B
OXYCODONE G01303M (MAb) G01304M (MAb) Y01299B
(BSA conj) (BSA conj)
Y01301B
BUPRENORPHINE G01291M (MAb) Y01291B
(BSA conj)
(BSA conj)
HS - High Sensitivity | B - Benzoylecgonine | C - Cocaine
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Therapeutic monitoring
CARBAMAZEPINE G31234M (MAb) Cyclosporin A G86313M (MAb)
DIGOXIN MAD53-310C (MAb) MAD53-122 (MAb) G45135M (MAb) G45330M (MAb)
THEOPHYLLINE MAD63-003 (MAb)
Antibiotics
ERYTHROMYCIN G13012M GENTAMICIN G55102M (MAb)
NEOMYCIN G13021M
(MAb BSA conj)
(MAb BSA conj)
TOBRAMYCIN MAD64-052 (MAb)
Other
DINITROPHENOL G01234M (MAb)
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Email: info@meridianlifescience.com Orders: orders@meridianlifescience.com www.meridianbioscience.com/lifescience
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