Immunoassays for drug-testing are generally divided into forensic (DOA assays) and clinical products (TDM serum assays). Due to the differences in applications there are distinct design, technical capabilities and regulatory approval processes for each type. Meridian offers a range of drug testing reagents designed to produce accurate and precise results for both qualitative and quantitative assays.
Drug Testing Reagents for Commercial Assay Development ANTIBODIES AND ANTIGENS DESIGNED FOR ASSAYS DETECTING THERAPEUTIC DRUGS AND DRUGS OF ABUSE
Immunoassays for drug-testing are generally divided into forensic (DOA assays) and clinical products (TDM serum assays). Due to the differences in applications there are distinct design, technical capabilities and regulatory approval processes for each type. Meridian offers a range of drug testing reagents designed to produce accurate and precise results for both qualitative and quantitative assays.
DRUG TESTING REAGENTS DRUGS OF ABUSE (DOA) Cannabinoids CNS stimulants Depressants Hallucinogens Opiates THERAPEUTIC MONITORING ANTIBIOTICS OTHER DRUG TESTING REAGENTS
Antibody & Conjugate Pairs MAbs suitable for rapid oral fluid or urine screening tests
About drug testing
Drug abuse testing traditionally refers to the practice of testing for drugs including depressants, hallucinogens, CNS stimulants, opiates, cannabinoids, and phencyclidine (PCP). These tests have expanded in recent years to include (1) workplace, military and school testing for drugs of abuse (DOA), (2) screening in sports for the use of performance enhancing compounds, and (3) the emergency-room in order to diagnose possible overdose situations. In all of these areas, the testing method is qualitative only and is typically dependent on a urine or saliva sample as the testing specimen. Specifically, these types of assays are designed to determine if an individual is or is not taking DOA or non-prescribed medications.
Another use of drug testing is to monitor drug pharmacokinetics in order to help physicians provide the best treatment to their patients. With most medications, a certain dosage level of the drug (the therapeutic range) is required to obtain the desired effect. The goal of therapeutic drug monitoring (TDM) is to optimize the dose and clinical outcome for each patient. Some key differences in the TDM testing method compared to DOA are (1) the diagnostic specimen is typically serum instead of urine, saliva or hair, (2) the results are quantitative and need to be accurate and precise over a large concentration range, and (3) the tests are designed for use in hospital laboratories as opposed to rapid point-of-care.
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Antibody & drug conjugate pairs
• All pairs are suitable for use in ELISA or Lateral Flow assays • Various conjugates available in different hapten: protein ratios
ANTIGEN CAPTURE
MAb DETECTION
ANTIGEN CAPTURE
MAb DETECTION
Y01301B (BSA) Y01287B (BSA) AMPHETAMINE
Y01298B (BSA) METHADONE
G01284M
G01301M or G01302M
G01282M or G01284M
METHAMPHETAMINE
BARBITAL
Y01294B (BSA)
G01295M or G01296M or G01297M
Y01285B (BSA)
G01283M or G01285M
BENZODIAZEPINE
MORPHINE
Y01290B (BSA)
G01290M
Y01295B (BSA 40:1) G01298M or G01299M or G01300M Y01296B (BSA 40:1) G01298M or G01299M or G01300M Y01297B (BSA 70:1) G01298M or G01299M or G01300M
BENZOYLECGONINE (MAIN COCAINE METABOLITE)
Y01293B (BSA)
G01294M or G01292M G01293M or G01292M
Y01292B (BSA)
BUPRENORPHINE
Y01291B (BSA)
G01291M
Y01299B (BSA) OXYCODONE
MDMA (ECSTACY)
G01303M or G01304M
Saliva & Urine
G01267B (BSA)
G01265M
THC
Y01268B (BSA)
G01286M
Illicit drugs
CANNABINOIDS
HALLUCINOGENS
BENZOYLECGONINE/ COCAINE G45020M (MAb) B G45132M (MAb)
THC MAD12-066 (MAb) G01286M (MAb) G01238M (MAb) G82920M (MAb) G82922M (MAb)
KETAMINE G01255M (MAb) G01269M (MAb) G01270M (MAb)
B+C B+C
G82911M (MAb) G01277M (MAb) G01292M (MAb) G01293M (MAb) G01294M (MAb)
Y01269B (BSA conj) Y01241B (BSA conj) Y01270B MDMA G01265M (MAb) G01266M (MAb) G01267B (BSA conj) DEPRESSANTS BARBITAL G01283M (MAb) G01285M (MAb) G01272M (MAb) Y01285B (BSA conj) PHENOBARBITAL Y82611A (BSA conj) BENZODIAZEPINE G01290M (MAb) Y01290B (BSA conj) Y01281B (BGG conj) Y01282B (BGG conj) Y01283B (BGG conj) Y01284B (BGG conj)
B+C B+C
Y01273B (BGG conj) Y01274B (BGG conj) Y01268B (BSA conj) PINACA (SYNTHETIC THC) Y01309B (BSA) K2 Y01302B (BSA conj)
(BSA conj) HS
B Y01292B (BSA conj) B Y01293B (BSA conj) B Y01277B (BSA conj) C COTININE G01257M (MAb) G01279M (MAb) Y01279B (BSA conj) COTININE-3 F82319R (PAb) COTININE-4 F82419R (PAb) F82451R (PAb) CAFFEINE G45110M (MAb) METHAMPHETAMINE
OPIATES
METHADONE G01301M (MAb) G01302M (MAb)
Y01280B (BGG conj) Y01298B (BSA conj) EDDP Y01306B (BSA conj) Y01305B (BGG conj) OPIUM Y01275B (BSA conj) PROPOXYPHENE Y01278B (BSA conj) MORPHINE
G35913M (MAb) G82913M (MAb) G01271M (MAb) G01295M (MAb) G01296M (MAb) G01297M (MAb)
CNS STIMULANTS
Y01294B (BSA conj) Y01271B (BSA conj)
AMPHETAMINE G82988M (MAb) G01282M (MAb) G01284M (MAb) G01289M (MAb)
G31263M (MAb) G01276M (MAb) G01298M (MAb) G01299M (MAb) G01300M (MAb)
Y01287B (BSA conj) Y01301B (BSA conj) BUPRENORPHINE G01291M (MAb) Y01291B (BSA conj) Y01235B (BSA conj)
Y01276B (BSA conj) Y01295B (BSA conj) Y01296B (BSA conj) Y01297B (BSA conj) OXYCODONE F82910R (PAb) G01303M (MAb) G01304M (MAb) Y01299B (BSA conj)
HS - High Sensitivity | B - Benzoylecgonine | C - Cocaine
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Therapeutic monitoring
CARBAMAZEPINE G31234M (MAb) CYCLOSPORIN A G86313M (MAb)
DIGOXIN MAD53-310C (MAb) MAD53-122 (MAb) G45135M (MAb) G45330M (MAb)
THEOPHYLLINE MAD63-003 (MAb) TRICYCLIC ANTIDEPRESSANTS G01288M (MAb) Y01288B (BSA conj)
Antibiotics
ERYTHROMYCIN G13012M GENTAMICIN G55102M (MAb)
NEOMYCIN G13021M
(MAb BSA conj)
(MAb BSA conj)
TOBRAMYCIN MAD64-052 (MAb)
Other
DINITROPHENOL G01241M (MAb) G01235M (MAb) G01234M (MAb)
Ordering information: USA 5171 Wilfong Road
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