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Top antigens and antibodies for cardiac immunoassasys Cardiac Products

Antibodies & Matched Pairs Brain Natriuretic Peptide (BNP), ProBNP + NT-ProBNP H86245M MAb to BNP ( Capture ), ELISA & WB H86507M MAb to BNP ( Detection ), ELISA & WB * Recognizes BNP. H86451M M Ab to NT-proBNP a.a. 61-76 (Capture) , ELISA & WB H86912M M Ab to NT-proBNP a.a. 1-12 (Detection) , ELISA & WB * Recognizes BNP, proBNP and NT-proBNP. K4A660R P Ab to BNP (Rabbit) ELISA, RIA, & IHC, lyophilized H01420M MAb to NT-proBNP a.a. 61-76 ( Capture ), ELISA & WB H01419M MAb to NT-proBNP a.a. 15-20 ( Detection ), ELISA & WB H01423M MAb to NT-proBNP a.a. 15-20 ( Alternate Detection ), ELISA & WB * Detects NT-proBNP and proBNP. H01422M MAb to NT-proBNP a.a. 5-12 (Capture) , ELISA & WB H01424M MAb to NT-proBNP a.a. 22-36 (Detection) , ELISA & WB * Detects NT-proBNP regardless of glycosylation. C-Reactive Protein (CRP) M86005M MAb (Capture) , ELISA M01239M MAb (Detection) , ELISA * Recognizes antigen in the presence and in the absence of Ca 2+ . Creatine Kinase (CK) MAC01-288 MAb to CK-BB, ELISA H31795M M Ab to CK-MB (Capture/Detection) , ELISA & LF K31315G P Ab (Goat) to CK-MM (Capture/Detection) , ELISA & LF * Abs can be used as capture or detection in a sandwich assay. MAC02-186 MAb to CK-MM, ELISA * 50% cross reactivity with CK-MB and < 1% cross reactivity with CK-BB. MAC02-512 MAb to CK-MM, ELISA * 52% cross reactivity with CK-MB, and no cross reactivity with CK-BB. Cystatin C H86023M MAb (Capture) , ELISA H86218M MAb (Detection) , ELISA H86013M MAb (Alternate Detection)

Fibrinogen N86413M Galectin-3 K01361M

MAb, ELISA & WB

MAb, ELISA, WB & IHC * Reacts with human and mouse Galectin-3. K01381M MAb, ELISA * Reacts with human and mouse Galectin-3. Glycogen Phosphorylase Isoenzyme BB (GPBB) H86807M MAb, ELISA & WB Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) H01390M MAb (Capture) , ELISA H01393M MAb (Detection) , ELISA H01389M MAb (Alternate Detection) , ELISA H01392M MAb (Capture) , ELISA H01393M MAb (Detection) , ELISA Myeloperoxidase (MPO) H87207M MAb, ELISA & IHC * Recognizes both native and recombinant human MPO. Myoglobin (MYO) H86142M MAb (Capture) , ELISA H86703M MAb (Detection) , ELISA H01328M MAb (Capture) , ELISA & LF H01327M MAb (Detection), ELISA & LF Procalcitonin (PCT) E86561M MAb (Capture) , ELISA & WB E86420M MAb (Detection) , ELISA & WB * Specific to procalcitonin and calcitonin. E86412M MAb (Capture) , ELISA E86813M MAb (Detection) , ELISA * Specific for procalcitonin and katacalcin. Pregnancy Associated Plasma Protein A (PAPP-A) E86141M MAb (Capture) , ELISA & WB E86910M MAb (Detection) , ELISA & WB * Detects both heterotetrameric (found in placental blood) and homodimeric (found in atherosclerotic plaques) PAPP-A. E86114M MAb, ELISA & WB S-Adenosyl-Homocysteine (SAH) K01395C PAb (Chicken), ELISA * Affinity purified, treated with Adenine-9--D-Ribofuranoside to remove cross reaction to Adenosine.

D-dimer N01265M N01273M N01274M N01270M N01269H

MAb, ELISA

MAb ( Capture ), ELISA & WB MAb ( Detection ), ELISA & WB MAb (Capture) , ELISA, LF & WB

MAb (Detection) , ELISA, LF & WB * Highly specific for D-dimer and other cross linked fibrin degradation products containing D-dimer, but no reactivity with Fragment D or E. No cross-reaction was found with purified intact fibrinogen or fibrinogen degradation products. N86304M MAb (Capture) , ELISA & WB N86352M MAb (Detection) , ELISA & WB * Reacts with high molecular weight fibrin degradation products. Does not cross react with fibrinogen or D-monomer. Fatty Acid Binding Protein (FABP) H01324M MAb (Capture) , ELISA & LF H01323M MAb (Detection) , ELISA & LF

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Antibodies & Matched Pairs continued Soluble CD40 Ligand (sCD40L) P86106M MAb, ELISA P42374M MAb, FC & IFA Troponin I-Cardiac (cTnI) H86285M M Ab to a.a. 86-90 (Capture) , ELISA &WB H01347M M Ab to a.a. 24-40 (Detection) , ELISA & WB * Reacts equally with free cTnI and complexed cTnI, does not cross react with sTn. H01340M MAb to a.a. 41-49, ELISA H86241M MAb to a.a. 87-91, ELISA &WB H86596M MAb to a.a. 169-178, ELISA &WB K31015M MAb (Capture) , ELISA K31341G P Ab to a.a. 27-39 (Goat, Detection) , ELISA, WB & IHC K31342G P Ab to a.a. 69-86 (Goat, Alternate Detection) , ELISA & IHC * Cross reactivity with sTn is < 0.1% (ELISA).

Troponin T-Cardiac (cTnT) H86429M

M Ab to a.a. 60-70 (Capture) , ELISA &WB M Ab to a.a. 95-181 (Detection) , ELISA & WB

H86111M

* Does not cross react with sTn. Vitamin D K01214M

MAb to Vitamin D (25 OH), ELISA, LF, CLIA & ELISA

* Pairs with antigens A01697B & A01698B. K01213M * Pairs with antigens A01697B & A01698B. K24124M-LQ

MAb to Vitamin D (25 OH), ELISA & RIA

MAb to 25-OH Vitamin D3, ELISA

K24124M K24123M

MAb to 25-OH Vitamin D3, ELISA

MAb to 1,25 (OH) 2 Vitamin D3, ELISA *Recognizes Native Human 25 OH Vitamin D2 and 25 OH Vitamin D3.

Human Antigens (for use as standards, controls & calibrators)

Brain Natriuretic Peptide (BNP), ProBNP + NT-ProBNP A24760H P roBNP, recombinant protein (E. coli) of N-terminal (a.a. 1-76, MW 8.39 kDa) A01261H N T-proBNP, recombinant protein (E. coli) of N-terminal (MW 8.589 kDa). Contains an additional methionine residue at the N-terminus (in comparison with native NT-proBNP) N86583H B NP and NT-proBNP Free Plasma, from normal human plasma, used for preparation of any proBNP-related standards and calibrators

Fibrinogen A95150H

F rom human plasma, MW 340kDa, isoelectric point of 5.1–6.3

Lp-PLA2 A01413H

Recombinant (E.coli) ,> 95% pure (SDS-PAGE)

Myeloperoxidase (MPO) A38104H

F rom human neutrophils, > 96% pure (SDS-PAGE), approximate activity of 1,100 Units/mg Protein

A97201H

Myoglobin A38131H

F rom human fluids and reactive with monospecific goat anti-CRP, 95% pure (SDS-PAGE)

From human heart, 99% pure (SDS-PAGE) Pregnancy Associated Plasma Protein A (PAPP-A) A86864H F rom human retroplacental blood. Heterotetrameric complex consisting of PAPP-A and pro-MBP subunits, > 85% pure (SDS-PAGE), lyophilized

Creatine Kinase (CK) VTI830

C K-BB, produced in cell culture (yeast), represents native full length protein and is enzymatically active C K-MB Isoenzyme Type I, produced in cell culture (yeast), enzymatically active CK-MB Isoenzyme Type II, produced in cell culture (yeast), represents native full length protein and is enzymatically active C K-MM Isoenzyme Type I, produced in cell culture (yeast), represents full length protein without the C-terminal lysine on both subunits and is enzymatically active C K-MM Isoenzyme Type III, produced in cell culture (yeast), represents full length protein and is enzymatically active

VTI840

Procalcitonin (PCT) A01367H

VTI810

Recombinant protein (E. coli) representing a.a. 3-116 which corresponds to the unprocessed human protein, contains a 6-His tag at N-terminal

VTI850

Troponin (cTnT & cTnI) A86111H

VTI820

I-T-C Complex, from human heart, formed by combining cardiac Troponin T, I and C in a molar ratio of 1:1:1 c TnT, from human heart, > 98% pure (SDS-PAGE) c TnI, from human heart, > 98% pure (SDS-PAGE), single band ~24 kDa

Cystatin-C A01259H

A86813H A38150H

From human urine, 95.5% pure

A01435H

F rom human urine, 95% pure (SDS-PAGE), major band at ~13 kDa, suitable for TIA applications

Vitamin D A01694D

D-Dimer A01408H A01463H

25-OH Vitamin D3 BSA Conjugate, ≥ 99% Pure (HPLC) Vitamin D Biotin Conjugate, > 95.7% Pure (HPLC)

From human plasma, > 90% pure

A01698B A01697B A50674H A01409H

From human plasma, > 95% pure (SDS-PAGE)

Vitamin D BSA Conjugate

Fatty Acid Binding Protein (FABP) A86865H

Vitamin D Binding Protein (Gc-Globulin), > 95% Pure (SDS-PAGE)

1,25 Dihydroxy Vitamin D3, > 99% Pure (HPLC)

From human heart, > 95% pure (SDS-PAGE)

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