Meridian offers in vitro cell culture and in vivo ascites production of monoclonal antibodies following ISO Quality Systems. Meridian’s flexible production systems accommodate milligram to kilogram projects.
• D edicated facility - 55,000 mice capacity • U p to 5,000 mice per lot • M ultiple strains available • A scites fluid or purified MAb service • H igh lot-to-lot consistency • C ustomized options (viability monitoring, mouse strain, yield optimization) In vivo
PRODUCTION SYSTEMS • T issue Culture & Spinner Flasks • R oller Bottles (smooth & ribbed) • WAVE Bioreactors™ CAPACITY • U p to gram quantities of pure MAb • C onversion from ascites to cell culture • A daption to serum free media • P ilot studies through to validation lots • Y ield and scale-up optimization • C ell-line rescue and sub-cloning PURIFICATION
• Protein A/G • SEC
• IEC • HIC
Powered by FlippingBook