GEN eBook - From Sample to Insight | Precision Oncology

From Sample to Insight: Technologies Driving the Future of Precision Oncology Assays

References 1. Tsimberidou, A. M., et al. (2020). Review of precision cancer medicine: Evolution of the treatment paradigm. Cancer Treatment Reviews, 86 , 102019. https://doi.org/10.1016/j. ctrv.2020.102019 2. Diamandis, E. P. (2010). Cancer biomarkers: Can we turn recent failures into success? Journal of the National Cancer Institute, 102 (19), 1462-1467. https://doi.org/10.1093/jnci/ djq306 3. The Cancer Genome Atlas Research Network, et al . (2013). The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genetics, 45 (10), 1113-1120. https://doi. org/10.1038/ng.2764 4. Passaro, A., et al. (2024). Cancer biomarkers: Emerging trends and clinical implications for personalized treat- ment. Cell, 187 (7), 1617-1635. https://doi.org/10.1016/j. cell.2024.02.041 5. Smith, A. (2022, August 26). From then to now: How genomic testing for cancer has expanded. Targeted Ther- apies in Oncology, 11 (11), 83. https://www.targetedonc. com/view/from-then-to-now-how-genomic-testing-for- cancer-has-expanded 6. Chan, C.-H., et al. (2023). PAK and PI3K pathway activation confers resistance to KRAS G12C inhibitor sotorasib. British Journal of Cancer, 128 (1), 148-159. https://doi.org/10.1038/ s41416-022-02032-w

7. Cancer Australia. (n.d.). Cancer continuum . Retrieved June 23, 2025, from https://ncci.canceraustralia.gov.au/ continuum 8. National Cancer Institute, Division of Cancer Control and Population Sciences. (n.d.). Cancer control continuum . U.S. Department of Health and Human Services. Retrieved June 23, 2025, from https://cancercontrol.cancer.gov/ about-dccps/about-cc/cancer-control-continuum 9. Zhuang, L., et al. (2025). Advancing Precision Oncology Through Modeling of Longitudinal and Multimodal Data. IEEE Reviews in Biomedical Engineering (Early Access). https://doi.org/10.1109/RBME.2025.3577587 10. Committee on Improving the Quality of Cancer Care: Addressing the Challenges of an Aging Population; Board on Health Care Services; Institute of Medicine. (2013, December 27). Delivering high-quality cancer care: Charting a new course for a system in crisis (L. Levit, E. Balogh, S. Nass, & P. A. Ganz, Eds.). National Academies Press. https:// doi.org/10.17226/18359 11. Agarwal, A., Ressler, D., & Snyder, G. (2015). The current and future state of companion diagnostics. Pharmacog- enomics and Personalized Medicine, 8 , 99-110. https://doi. org/10.2147/PGPM.S49493

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Advancing Precision Medicine: Innovative qPCR & Genotyping Chemistries for Enhanced Assay Performance Boost the sensitivity, speed, and specificity of your assays with innovative qPCR and genotyping chemistries engineered for precision medicine... Download the brochure to explore our solutions .

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