Molecular Overview

molecular reagents

Cutting-edge master mixes, enzymes and reagent solutions for MDx assays.

master mixes tailored for your assays

Direct Detection

Skip DNA or RNA extraction

Specimen-specific or Universal options

Blood Saliva Stool

Urine Plant

Universal

Inhibitor-Tolerant

Methodology

Optimized for sensitive & robust amplification from crude samples

Direct Detection

DNA/RNA Extraction

Ultra-Sensitive

Technology

Detect down to single copies of DNA or RNA

qPCR LAMP

Final assay format

Cost-Efficiencies

Improve cost of final test with no extraction, no cold-chain shipping/ storage & faster R&D development

Lyophilized

Air-Dry

Liquid

All products are made under ISO13485 in commercial scales and are in hundreds of regulated assays around the world.

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qPCR & LAMP master mixes

general reagents

• Air-Dryable TM Direct DNA & DNA/RNA qPCR Blood (MDX092 & MDX121) • Lyo-Ready TM Direct DNA & DNA/RNA qPCR Blood (MDX122 & MDX123) • Lyo-Ready TM Direct DNA & DNA/RNA LAMP Blood (MDX124 & MDX125) Blood • Air-Dryable TM Direct DNA & DNA/RNA qPCR Saiva (MDX130 & MDX131) • Lyo-Ready TM Direct DNA & DNA/RNA qPCR Saliva (MDX132 & MDX133) • Lyo-Ready TM Direct DNA & DNA/RNA LAMP Saliva (MDX134 & MDX135) Saliva • Air-Dryable TM Direct DNA & DNA/RNA qPCR Urine (MDX150 & MDX151) • Lyo-Ready TM Direct DNA & DNA/RNA qPCR Urine (MDX152 & MDX153) • Lyo-Ready TM Direct DNA & DNA/RNA LAMP Urine (MDX154 & MDX155) Urine • Air-Dryable TM Direct DNA & DNA/RNA qPCR Stool (MDX140 & MDX141) • Lyo-Ready TM Direct DNA & DNA/RNA qPCR Stool (MDX142 & MDX143) • Lyo-Ready TM Direct DNA & DNA/RNA LAMP Stool (MDX144 & MDX145) Stool

VLP-RNA Extraction Controls (MDX068 & MDX069) • Biomimetic controls composed of virus-like particle (VLP) shells packaged with a defined number of copies of target RNA molecules. • Monitor extraction, reverse transcription and amplification with a single control. qPCR/RT-qPCR Extraction Controls (MDX026, MDX027, MDX028 & MDX029) • Artificial cells containing a known concentration of either Internal Control DNA or RNA sequences (that have no known homology) • Genetic material from the test sample and the DNA or RNA extraction control are simultaneously extracted by common extraction methods • Internal controls confirm the success of the extraction step and reduce the chance of obtaining a false negative result dNTPs • Sodium or lithium salt • Available as mixes or individually in various concentrations

• Air-Dryable TM Direct DNA qPCR Plant Mix (MDX116) Plant

Universal

• Inhibitor-Tolerant qPCR & RT-qPCR Mixes (MDX013 & MDX016) • Fast qPCR & RT-qPCR Mixes (MDX020 & MDX032) • Air-Dryable TM qPCR & RT-qPCR Mixes (MDX082 & MDX095) • Lyo-Ready TM qPCR & RT-qPCR Mixes (MDX021 & MDX024) • Air-Dryable TM DNA & RNA LAMP Mixes (MDX119 & MDX118) • Lyo-Ready TM DNA & RNA LAMP Mixes (MDX097 & MDX108) • Low LOD 1-Step RT-qPCR Mix (MDX025)

What is Air-Dryable?

Air-Dryable mixes are a new alternative to lyophilization. Create ambient temperature stable assays using only an oven.

enzymes

Reverse Transcriptase • 55C MMLV-RT (MDX117) Isothermal Amplification • High-Conc. Glycerol-Free Bst, 100x (MDX018) • Bst DNA Polymerase (MDX012) Next-generation Sequencing • Hi-Specificity Pfu HS Mix (MDX003)

DNA Polymerase • Taq HS DNA Polymerase (MDX008) • Low DNA Taq HS 5 U/ L (MDX009) • Glycerol-Free Taq HS 50 U/ L (MDX011) • Aptamer Taq HS (Glycerol-Free) (MDX015)

Learn more

Ordering information: USA 5171 Wilfong Road Memphis, Tennessee 38134 Phone: +1 901-382-8716 Fax: +1 901-333-8223

Email: info@meridianlifescience.com Orders: orders@meridianlifescience.com www.meridianbioscience.com/lifescience

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ISO 13485 Certified

07/22

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