Viral Hepatitis

REAGENTS FOR SEROLOGY TESTING

Hepatitis C core antigen can be detected soon after infection, before the development of antibodies to the virus, and remains detectable throughout chronic infection. Evaluations in transfusion settings have shown that the HCV Core Ag assay detects HCV infection as effective as NAT, about 40-50 days earlier than the current third generation anti-HCV screening assays. HCV core antigen levels closely follow HCV RNA dynamics, and allow clinical monitoring of a patient’s therapy, independently of HCV genotype. HCV Core Antigen Test

BN1102

MAb to HCV

• Isotype IgG1, kappa • Capture antibody

BN1101

MAb to HCV

• Isotype IgG2a, kappa • Detection antibody

Paired MAbs for Sandwich ELISA and Lateral Flow Antigen Detection Assays

C01253M

MAb to HCV

• Reactive with genotypes 1a and 2 • Isotype IgG1 • Capture antibody

MAb to HCV

C65317M

• Recognizes amino acids 33-38 of HCV core antigen • Isotype IgG1 • Detection antibody

MAb to HCV

C65185M

• Specific for a structural sequence of HCV core protein • Isotype IgG1 • Recognizes amino acids 70-90 of HCV core antigen • Isotype IgG1 • Recognizes amino acids 1-80 of HCV core antigen • Isotype IgG2a • Suitable for use in ELISA employing native viral lysates

C8A216M

Suitable for ELISA Antigen Detection Assays

C8A016M

C11423M

• Reacts with an epitope located between amino acids 36 and 115 of the HCV core antigen • Isotype IgG1