Blood Donor Screening

Universal Screening

HBV WHO Recommended: EIA or CLIA assay for Hepatitis B surface antigen (HBsAg). Anti-Hepatitis B core antigen (HBcAg) assays can also be used as an additional marker in some countries with low HBV prevalence. Recombinant Antigens VTI610 Hepatitis B Core Virus (HBcAg), P. pastoris Entire sequence of core protein (a.a.183) Antibodies C18286M MAb to HBsAg (ad/ay), pair C18212M MAb to HBsAg (ad/ay), pair C01247M MAb to HBsAg (ad/ay), pair C01248M MAb to HBsAg (ad/ay), pair B65811R Rabbit anti-HBsAg (ad/ay), pair HCV WHO Recommended: EIA or CLIA assay for HCV antibodies (typically against the antigens NS3, NS4 NS5 and HCV core). Recombinant Antigens VTI710 HCV Core, P. pastoris R01518 HCV NS-3 c33c Genotype 1a, E. coli Contains the main immunodominant region of HCV c33c /NS3 (a.a. 1192-1459) R8A116 HCV NS-4a+b, E. coli Contains a.a. 1658-1863 of the NS4 protein R18190 HCV NS-5 Genotype 1, E. coli Contains a.a. 2212-2313 of the NS5 protein R18523 HCV Nucleocapsid NS3/NS4/NS5, E. coli Contains immunodominant regions of the core, NS3, NS4 and NS5 proteins R01599 HCV Core NS3/NS4/NS5, E. coli Contains core fragment (a.a. 11-45), NS3 fragment (a.a. 1208-1430), NS4 fragment (a.a. 1885-1923), NS5 fragment (a.a. 2332-2423). Works as a capture antigen in a pair with R01600 R01600 HCV Core NS3/NS4/NS5, E. coli Contains core fragment (a.a. 11-53), NS3 fragment (a.a. 1210-1450, 1337-1483), NS4 fragment (a.a. 1888-1925), NS5 fragment (a.a. 2332-2423). Works as a detection antigen in a pair with R01599

HIV-1 & HIV-2 WHO Recommended: EIA or CLIA assay for HIV-1, 2 and Type O antibodies, can be used in combination of with HIV-1 p24 antigen detection. Recombinant Antigens R01593 HIV-1 C-Terminal gp120 + most of gp41, E. coli Reacts with all sera of HIV-1 and HIV-type O infected individuals and with 60-80% of HIV-2 infected individuals R01454 HIV-1 gp41 Type O, E. coli Reacts with human HIV type O positive serum VTI360 HIV-2 gp36, P. pastoris Contains a.a. 2212-2313 of the NS5 protein Antibodies C01653M MAb to HIV-1 p24, pair C01655M MAb to HIV-1 p24 , pair C65690M MAb to HIV-1 p24 , pair Treponema pallidum (Syphilis) WHO Recommended: EIA assay for specific treponemal antibodies (typically p15, p17, p42.5, p47 or TmpA). Recombinant Antigens R01681 T. pallidum p15/p17/p47, E. coli Works in double antigen sandwich immunoassays with R01682 as the detection antigen R01682 T. pallidum p15/p17/p47, E. coli Works in double antigen sandwich immunoassays with R01681 as the capture antigen R01705 T. pallidum p17/p15/p42.5/p47, E. coli Chimeric protein that contains fragments of p17, p15, p42.5 and p47 R01582 T. pallidum p15, E. coli Contains a GST- and His-tag at the N-terminus R01583 T. pallidum p17, E. coli Contains a GST- and His-tag at the N-terminus R8A201 T. pallidum p17, E. coli Contains Beta-galactosidase fused at the N-terminus R01606 T. pallidum p47, E. coli Contains a GST- and His-tag at the N-terminus R8A403 T. pallidum p47, E. coli Contains Beta-galactosidase fused at the N-terminus R01665 T. pallidum TmpA, E. coli Represents mature TmpA without the leader peptide. Contains a GST- and His-tag at the N-terminus R8A404 T. pallidum TmpA, E. coli Contains Beta-galactosidase fused at the N-terminus