SARS-CoV-2 High Sensitivity Antibodies
For Rapid Antigen Detection Assays
Rapid antigen tests can provide a result in minutes and can be produced at a lower cost in large scales. However, the performance of a rapid antigen test is limited by the sensitivity of the antibodies used. Meridian’s monoclonal antibodies are highly sensitive for the detection of SARS-CoV-2 and they do not cross-react with seasonal coronavirus strains. They are ideal for developing reliable and sensitive rapid lateral flow antigen assays for the detection of active COVID-19 infections.
NUCLEOCAPSID ANTIBODIES
Detects omicron variant down to 1.31 x 10 2 PFU/mL and all other variants down to 1.88 x 10 2 PFU/mL in clinical samples Used in both FDA EUA and CE-marked kits Validated for lateral flow & ELISA >95% purity (Protein G) Does not cross-react with other coronaviruses, except SARS (2003)
Capture Antibody:
9548
MAb to SARS-CoV-2 NP
*pairs with both detection antibodies 9547 and 9549
Detection Antibody:
9547
MAb to SARS-CoV-2 NP
9549
MAb to SARS-CoV-2 NP
Cat# 9548/9547 detects variant strains Alpha B.1.1.7, Beta B.1.351, Gamma P.1/P.2 , Delta B.1.617.2 and Omicron B.1.1.529
TRIMERIC SPIKE ANTIBODIES
Capture Antibody:
For use in lateral flow antigen detection COVID-19 assays with a trimetric spike recombinant antigen as control (e.g: Cat# 9566) Designed to work on saliva samples (no lysis required) Novel antibody pair to the trimeric form of the Spike 1 surface glycoprotein, recognizes both the G614 and D614G strains Using a mixture of detection antibodies Cat# 9565 and #9551 in a 1:1 ratio creates a synergistic effect that increases assay sensitivity in ELISA Recognizes a linear epitope - binding is not conformation-dependent Sensitivity of approx. 300 pg/mL in ELISA Does not cross-react with SARS-CoV, HCoV-229E, HCoV-HKU1, HCoV-NL63 and HCoV-OC43
9550
MAb to SARS-CoV-2 S1 (Trimeric)
Detection Antibody:
9551
MAb to SARS-CoV-2 S1 (Trimeric)
9565
MAb to SARS-CoV-2 S1 (Trimeric)
*9551 and 9565 can be used together in a 1:1 ratio to increase assay sensitivity in ELISA
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