Product list | Continued
BN1137
• NT-proBNP, recombinant, MBP tag (E. coli) • >70% (SDS-PAGE) • NT-proBNP, recombinant, C-terminal His-tag (HEK) • >90% (SDS-PAGE) • NT-proBNP, recombinant, C-terminal His-tag (HEK) • proBNP recombinant (E. coli) • Suitable for enzyme linked fluorescent assay • 95% pure (Silver Staining SDS-PAGE)
BNP, ProBNP & NT-ProBNP BNP (B type natriuretic peptide) is a hormone and important biomarker with an established role in the diagnosis of congestive heart failure. Its utility has also been explored in myocardial ischemia and infarction, and in acute pulmonary embolism. When BNP is secreted it is attached to a 76–amino acid N-terminal fragment called NT-proBNP which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor (ANP) receptors. Monoclonals • Reacts with proBNP, N-terminal • Suitable for proBNP and NT-proBNP immunoassay BN1095 • Ideal for lateral flow BN1096 • Ideal for lateral flow H86705M a.a. 13-27 H86010M a.a. 28-45 *Also works in WB H86916M a.a. 46-60 *Also works in WB H86288M a.a. 61-76 Antibody Pairs • Suitable for use in ELISA and WB • Specific for Human BNP unless otherwise specified CAPTURE DETECTION H86051M H86262M
BN1138
BN1139 R01614
A24108H
• proBNP recombinant (E. coli) • > 95% pure (SDS-PAGE)
A01455H
• proBNP recombinant (E. coli) • Suitable for use in ELISA as a calibrator, standard or an immunogen for antibody development
• Contains one additional Methionine residue at the N-Terminus (in comparison with native proBNP) • > 95% pure (Tricine SDS-PAGE)
A24810H
• proBNP, C-terminal (synthetic) • Represents amino acids 1-32 • > 95% pure (HPLC), lyophilized
A24607H
• proBNP, N-terminal recombinant (synthetic) • Represents a.a.1-76 • > 95% pure (HPLC), lyophilized • proBNP, N-terminal recombinant (E. coli) • Represents the N-terminal a.a.1-76 • > 95% pure (SDS-PAGE), lyophilized • NT-proBNP recombinant (E. coli) • > 95% pure (Silver Staining SDS-PAGE) • Suitable for enzyme linked fluorescent assay
H86051M H01365M H01365M H86507M H01365M H86573M H01365M H01366M H86051M H86915M
A24760H
*Recognizes BNP & pro-BNP
R01616
*Recognizes pro-BNP
H86451M
H86132M
*Recognizes proBNP & NT-proBNP *Recognizes proBNP & NT-proBNP *Recognizes proBNP & NT-proBNP *Recognizes proBNP & NT-proBNP *Detects NT-proBNP and proBNP *Detects NT-proBNP and proBNP *Detects NT-proBNP and proBNP
H86451M H86912M H86451M H86915M H86511M H86214M H01420M H01422M H01420M H01419M H01420M H01423M
A01261H
• NT-proBNP recombinant (E. coli) • Suitable for use in ELISA • > 95% pure (Tricine SDS-PAGE) • >90% (SDS-PAGE)
BN1095
BN1096
Carboxy Methyl Lysine (CML) A well-characterized glycoxidation product, formed from the oxidation of both carbohydrates and lipids, which accumulates in tissues with age. CML is a biomarker of general oxidative stress which is involved in the pathogenesis of atherosclerosis. Polyclonals CATALOG SOURCE FORMAT APPLICATION K97135G Goat Aff. Pur. EIA,WB
Polyclonals CATALOG
SOURCE FORMAT APPLICATION
K4A660R Rabbit K4A670R Rabbit K24410R Rabbit
Neat
EIA,IFA,IHC,RIA
Purified
EIA,IHC,RIA
Neat
RIA
Antigens
BN1136
• NT-proBNP, recombinant, N-term His-Tag (E. coli) • >90% (SDS-PAGE)
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8 | Cardiac & Metabolic Markers for Assay Development Cardiac & Metabolic Markers for Assay Development
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