Cancer & Tumor Markers Catalog

CAPTURE DETECTION M86520M M86101M M86406M M86101M M86416M M86101M M86141M M86201M M86101M M86520M Antigens A86803H

Monocyte Chemotactic Protein 1 (MCP-1 or CCL2) MCP-1 is a small cytokine that recruits monocytes, memory T-cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Increased MCP-1 serum levels have been seen in patients with various cancers and has been suggested to be a prognostic marker for solid tumors. It may also be a helpful tumor marker of prognosis in patients with digestive cancer, urogenital cancers, and head and neck cancers. Antigens A01251H • Recombinant (E. coli) • > 98% pure (RP-HPLC & SDS-PAGE), lyophilized Neutrophil Gelatinase-Associated Lipocalin (NGAL)/Lipocalin-2 NGAL is a secreted carrier protein that acts in the innate immune response and is used as a biomarker of kidney injury. It also functions as a growth factor and is highly expressed in early dysplastic lesions in the pancreas, suggesting a possible role as an early diagnostic marker for pancreatic cancer. In addition, serum NGAL might be a possible biomarker in pancreatitis and pancreatic adenocarcinoma. Polyclonals CATALOG SOURCE FORMAT APPLICATION K01392C C. Eggs Aff.Pur. N/A Antigens 9278 • Recombinant (CHO cells)

• Native antigen from human brain • Subunit composition is gamma-gamma

• Suitable for use in ELISA • > 95% pure (SDS-PAGE)

A01359H

• Recombinant (E. coli) • Represents a.a. 2-434, contains a His-tag • Suitable for use in ELISA, LF, WB, DB, and IHC • > 95% pure (SDS-PAGE) • Recombinant (E. coli) • Represents a.a. 1-434, contains a His-tag

A01448H

• Suitable for use in ELISA • 95% pure (SDS-PAGE)

Osteopontin (OPN) OPN is an extracellular matrix protein involved in the regulation of normal mineralization in bone and teeth and is an important factor in bone remodeling. Various human cancers, including breast cancer, have been observed to express splice variants of OPN. Studies have shown that it is significantly associated with survival in several forms of cancer, suggesting its value as a clinical marker of tumor progression. Monoclonals

• Suitable for use in WB • 95% pure (SDS-PAGE)

Neuron Specific Enolase (NSE) gamma NSE is a glycolytic enzyme that catalyzes the conversion of phosphoglycerate to phosphoenol pyruvate and is the dominant enolase-isoenzyme found in neuronal and neuroendocrine tissues. NSE can be used to monitor disease progression and management in small cell lung cancer, and as an independent predictor of survival of non-small cell lung cancer. Antibody Pairs • Specific for the gamma subunit, no cross-reactivity with alpha or beta subunits • Suitable for use in ELISA • Produced in vivo

• Specific to N-terminal (a.a. 1-166) • Suitable for use in ELISA and WB • Produced in vivo M66102M Antibody Pairs • Suitable for use in ELISA and WB • Produced in vivo CAPTURE DETECTION M66103M M66105M

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