Cancer & Tumor Markers Catalog

Product list | Continued

S-100 The S-100 family of proteins are involved in the regulation of a number of cellular processes including cell cycle progression and differentiation. Dysregulated expression of several S100 proteins is a common feature of human cancers, with each type of cancer showing a unique S100 protein profile. S-100 is suggested to be a diagnostic marker for differentiating amelanotic malignant melanomas end may also aid the detection of micrometastatic disease in the lymph nodes of melanoma patients. Monoclonals • Produced in vivo MEM24-211 * Works in IHC Q86403M * Recognizes S-100 (beta-beta) and S-100 (alpha-beta), works in WB Antibody Pairs • Suitable for use in ELISA and IP • MAbs produced in vivo CAPTURE DETECTION Q86006M Q86610M * Specific for S-100 beta-beta and alpha-beta Q86003M Q86610M * Specific for S-100 beta-beta Antigens A86809H • Native antigen from human brain • Contains beta-beta homodimer (S-100b) and alpha-beta heterodimer (S-100a) • Suitable for ELISA, for antibody production or as tracer for iodination • > 95% pure, lyophilized A86289H • Native S-100b homodimer from human brain • Suitable for ELISA, for antibody production or as tracer for iodination • > 95% pure, lyophilized

Serum Amyloid A (SAA) SAA is a sensitive marker of acute inflammation that is synthesized under the regulation of inflammatory cytokines during both acute and chronic inflammation. Increases in serum levels of SAA correlate with many types of carcinogenesis and neoplastic diseases. Specifically SAA has been suggested to be a potential tumor marker for renal cancer, lung cancer and uterine cervical cancer. Antibody Pairs • Recognizes native and recombinant human SAA • Suitable for use in ELISA and WB • MAbs produced in vivo CAPTURE DETECTION H01381M H01383M H01382M H01384M Polyclonals CATALOG SOURCE FORMAT APPLICATION H01379R Rabbit Purified ELISA,IEP Antigens R01619 • Recombinant (E. coli) • 122 a.a. long with N-terminal His tag • Suitable for use in ELISA structurally related carbohydrate structures used as markers of cell differentiation and embryonic development. Sialyl Lewis A and Sialyl Lewis X are specifically tumor-associated and involved in adhesion and metastatic potential of cancer cells. They are being used to identify new cancer biomarkers through antibody arrays paired with a glycan specific antibody to probe the bound glycoproteins, in identifying new ways to target cancer cells for therapy. Monoclonals • Produced in vivo Sialyl Lewis A and Sialyl Lewis X Lewis blood group antigens are biosynthetically and

MAM10-810 * Specific for Sialyl Lewis A MEM11-767 * Specific for Sialyl Lewis X

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22 | Cancer & Tumor Markers for Assay Development

Cancer & Tumor Markers- Reagents for Assay Development

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