Molecular Overview

Cutting-edge master mixes, enzymes and reagent solutions for MDx assays.

Cutting Edge Raw Materials to Support All Your Assay Needs Molecular Dx Made Easy

master mixes tailored for your assays

Direct Detection

Skip DNA or RNA extraction

Specimen-specific or Universal options

Blood Saliva Stool

Urine Plant

Universal

Inhibitor-Tolerant

Methodology

Optimized for sensitive & robust amplification from crude samples

Direct Detection

DNA/RNA Extraction

Ultra-Sensitive

Technology

Detect down to single copies of DNA or RNA

qPCR

LAMP

NASBA

Final assay format

Cost-Efficiencies

Improve cost of final test with no extraction, no cold-chain shipping/ storage & faster R&D development

Lyophilized Air-Dry

Liquid

All products are made under ISO13485 in commercial scales and are in hundreds of regulated assays around the world.

meridianbioscience.com/lifescience

qPCR & LAMP master mixes

general reagents

Blood

VLP-RNA Extraction Controls (MDX068 & MDX069) • Biomimetic controls composed of virus-like particle (VLP) shells packaged with a defined number of copies of target RNA molecules. • Monitor extraction, reverse transcription and amplification with a single control. qPCR/RT-qPCR Extraction Controls (MDX026, MDX027, MDX028 & MDX029) • Artificial cells containing a known concentration of either Internal Control DNA or RNA sequences • Designed to confirm the success of the extraction step and reduce the chance of obtaining a false negative result dNTPs • Sodium or lithium salt • Available as mixes or individually in various concentrations

• Air-Dryable TM Direct qPCR & RT-qPCR Mixes Blood (MDX092/121) • Lyo-Ready TM Genotyping Direct qPCR Blood (MDX128) • Lyo-Ready TM Direct qPCR & RT-qPCR Mixes Blood (MDX122/123) • Lyo-Ready TM Direct DNA & RNA LAMP Mixes Blood (MDX124/125) • Air-Dryable TM Direct qPCR & RT-qPCR Mixes Saliva (MDX130/131) • Lyo-Ready TM Direct qPCR & RT-qPCR Mixes Saliva (MDX132/133) • Lyo-Ready TM Direct DNA & RNA LAMP Mixes Saliva (MDX134/135) Saliva

Stool

• Air-Dryable TM Direct qPCR & RT-qPCR Mixes Stool (MDX140/141) • Lyo-Ready TM Genotyping Direct qPCR Stool (MDX148) • Lyo-Ready TM Direct qPCR & RT-qPCR Mixes Stool (MDX142/143) • Lyo-Ready TM Direct DNA & RNA LAMP Mixes Stool (MDX144/145)

Urine

• Air-Dryable TM Direct qPCR & RT-qPCR Mixes Urine (MDX150/151) • Lyo-Ready TM Genotyping Direct qPCR Urine (MDX158) • Lyo-Ready TM Direct qPCR & RT-qPCR Mixes Urine (MDX152/153) • Lyo-Ready TM Direct DNA & RNA LAMP Mixes Urine (MDX154/155)

enzymes

• Air-Dryable TM Direct DNA qPCR Plant Mix (MDX116) Plant

Reverse Transcriptase • 55C MMLV-RT (MDX117) • Glycerol-Free AMV-RT (HC) (MDX209) Isothermal Amplification • High-Conc. Glycerol-Free Bst, 100x (MDX018) • Bst DNA Polymerase (MDX012) • Glycerol-Free T7 RNA Polymerase (HC) (MDX201) • Glycerol-Free RNase H (HC) (MDX202) Next-generation Sequencing • Hi-Specificity Pfu HS Mix (MDX003) • Glycerol-free T4 DNA Ligase HC (MDX200) DNA Polymerase • Taq HS DNA Polymerase (MDX008) • Low DNA Taq HS 5 U/ L (MDX009) • Glycerol-Free Taq HS 50 U/ L (MDX011) • Aptamer Taq HS (Glycerol-Free) (MDX015)

Universal

• Inhibitor-Tolerant qPCR & RT-qPCR Mixes (MDX013 & MDX016) • Fast qPCR & RT-qPCR Mixes (MDX020 & MDX032) • A ir-Dryable TM qPCR & RT-qPCR Mixes (MDX082 & MDX095) • L yo-Ready TM qPCR & RT-qPCR Mixes (MDX021 & MDX024) • Low LOD 1-Step RT-qPCR Mix (MDX025) • A ir-Dryable TM DNA & RNA LAMP Mixes (MDX119 & MDX118) • Lyo-Ready TM DNA & RNA LAMP Mixes (MDX097 & MDX108)

Ordering information: USA 5171 Wilfong Road Memphis, Tennessee 38134 Phone: +1 901-382-8716 Fax: +1 901-333-8223

Email: info@meridianlifescience.com Orders: orders@meridianlifescience.com www.meridianbioscience.com/lifescience

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ISO 13485 Certified

10/23

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