Cancer & Tumor Markers Catalog

Cancer Antigen 125 (CA125) A protein in humans that is encoded by the MUC16 gene and found on the surface of many ovarian cancer cells. Monitoring CA125 blood serum levels is also useful for determining how ovarian cancer is responding to treatment and for predicting a patient’s prognosis after treatment. CA125 can also be found in other cancers and in small amounts in normal tissue. Antibody Pairs

Cancer Antigen 15-3 (CA15-3 or MUC1) CA15-3 is a tumor marker which corresponds to an immuno- dominant epitope in the extracellular portion of the membrane bound mucin MUC1. It is used to monitor a patient’s response to breast cancer treatment and disease recurrence. CA15-3 and the associated CA27.29 are different epitopes on the same gene product. Antibody Pairs • Binds to an epitope within the VNTR tandem repeat peptide region of MUC1 • Suitable for use in ELISA and IHC • MAbs produced in in vivo CAPTURE DETECTION SPECIFIC FOR CA15-3 M86240M M01289M * Underglycosylated M86240M M86240M * Unglycosylated Antigens A32231H • Low cross-reactivity ideal for multi-analyte panels • Suitable for use as a calibrator or control • Suitable for use in CLIA • Cell culture derived protein from human BTA cell line A86153H • Native antigen from human milk

• Detects both Group A and Group B • Suitable for use in ELISA and WB • MAbs produced in in vivo CAPTURE DETECTION M86306M M86924M M86306M M86429M Monoclonals • Suitable for use in ELISA and WB • MAbs produced in vivo M86306B

* Specific to Group A, biotin conjugated * Specific to Group B, biotin conjugated

M86429B Antigens A01693H

• Ovarian Cancer, Calibrator Grade • Low cross-reactivity

• Suitable for use as a calibrator or as an immunogen for antibody development • Suitable for use in CLIA and WB • Cell culture derived protein from human BTA cell line • Native antigen from human fluids • High purity (relative Purity Ratio: > 20,000 Units/mL/OD280nm) • Suitable for use in ELISA and WB

A32180H

• Suitable for use as a calibrator for single or multiple analyte controls • Low cross-reactivity ideal for multi-analyte panels • Cell culture derived protein

A32000H

A97180H

• Cell culture derived protein from ovarian carcinoma cell line • Suitable for use in WB and RIA • Cell culture derived protein from human adenocarcinoma cell line • Suitable for use as a calibrator • Cell culture derived protein from human adenocarcinoma cell line • Suitable for use as a calibrator • > 50% pure (SDS-PAGE) • Partially pure antigen from human fluids • Low cross-reactivity • Suitable for use in ELISA and Electrochemiluminescence assay as a calibrator or control

A01436H

A86125H

Please note that cell culture derived antigens offer several advantages over the native fluid versions, including greater availability of the product.

A86928H

A01690H

Please note that cell culture derived antigens offer several advantages over the native fluid versions, including greater availability of the product.